This is an excellent excerpt reprinted with permission from Burke's book, High-Tech Cycling-2nd Edition.
"Most studies examining pedaling cadence have focused on pedal optimization in terms of economy/efficiency and local muscle stress. In this section, we will summarize the findings of the numerous laboratory studies that have attempted to identify which cadence is optimal. Unfortunately, few investigations have analyzed the question in well-trained cyclists riding their own bikes, making it difficult to apply the findings to actual cycling.
Optimal Cadence and Oxygen Cost: Economy/Efficiency
The two main messages to emerge from the numerous studies published since the beginning of the 20th century are as follows:
A detailed look at the published studies suggests that both general conclusions need to be approached with caution. Several factors may alter the optimal and preferred pedaling cadence, including absolute and/or relative power output (i.e., watts or percentage maximal oxygen uptake [V·O2max], respectively), duration of exercise, test mode (cycle ergometer tests versus riding a bicycle on a treadmill), fitness level of the subject (cyclist or noncyclist), and the high interindividual variability, even among trained cyclists of similar fitness levels, reported by most authors.
In general, during laboratory tests performed by noncyclists at constant power outputs (usually = 200 W), pedaling at low rates (~ 50 to 70 rpm) resulted in